WCD 26 - K-VANI Blog _ Dr. Paul Sebastian - 1777 x 1000 – 2 (2)

The Convergence of Equity and Precision: Redefining the Cancer Journey

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The Convergence of Equity and Precision: Redefining the Cancer
Journey

Dr. Paul Sebastian, a veteran in oncology, clinical governance and population-level cancer
programs
During more than forty years of working in cancer care—as a surgeon, researcher, and leader of an institution like the Regional Cancer Centre (RCC), Trivandrum—I have believed in one simple idea: where a person lives or how much they earn should not decide their chance of surviving cancer. Yet, for many patients today, a cancer diagnosis still means navigating a confusing and disconnected health system, often alone.
Around the world, cancer leaders speak about equity and closing the care gap. These goals are important, but they cannot be achieved by good intentions alone. Real equity needs strong systems that work on the ground. At Karkinos Healthcare, we are building such a system by combining advanced science like genomics with strong patient support. Our aim is simple: to ensure that every patient is guided, supported, and never left to face cancer alone.

From Excellence in Institutions to Distributed Care

During my time working at the state level, my focus was on elevating RCC to a State Cancer Institute and establishing it as a centre of excellence for teaching and training in all disciplines of oncology and allied sciences. We created excellence within the hospital. However, my later work in public health with a philanthropic organisation made one thing clear: excellence must go beyond hospital walls. It must reach people in remote villages and underserved urban areas.
This is the core of the Karkinos philosophy. We are breaking the idea that world-class cancer care can exist only in big city hospitals. By connecting diagnostics, hospitals, and specialists through a distributed network, we ensure that expert opinions—such as those from multidisciplinary tumour boards—are available to patients wherever they live.

Patient Navigation and the Command Centre

In my previous role of leading public health and palliative care programmes, where I oversaw the roll-out of cancer outreach programs across several states, I witnessed first-hand how easily patients can be lost in a fragmented system—missing appointments, delaying treatment, or stopping care altogether. Compassion alone cannot fix this. What is needed is structure and coordination.

At Karkinos Healthcare, we have engineered a technology-led solution to provide this coordination : the Command Centre. Functioning as the digital backbone of our patient navigation system, the Command Centre acts as the central control system for a patient’s entire cancer journey. The Command Centre tracks each step of care in real time, coordinates diagnostics and treatmentacross hospitals, and ensures that patients receive timely guidance. This means the burden of managing cancer care is taken off the patient and handled by the system instead. This technology is vital to our mission of providing affordable, accessible, and equitable cancer care to all, guaranteeing that expert guidance is available at every turn, effectively ensuring that no one walks alone.

The Science of Equity: Democratising Genomics

For many years, my research has focused on developing cancer treatments that are effective and
affordable for countries with limited resources. There is a common belief that low-cost care must
also be low-technology. This is however not true. Advanced tools like genomic testing and precision
medicine actually reduce costs. By understanding the exact biology of a patient’s cancer early, we
can choose treatments that are more likely to work and avoid unnecessary, ineffective therapies.
This saves time, money, and patients from avoidable side effects. In this way, advanced science
becomes a powerful tool for equity—helping us deliver better care to more people, with fewer
wasted resources.
At Karkinos, we are democratising access to these advanced tools. We are applying the rigour of
international research to ensure that precision oncology is an accessible standard, not a luxury
good.

The “Early” Imperative and Women’s Wellness

As a head and neck surgeon, I have repeatedly witnessed the human cost of cancers detected too
late—especially oral cancers in younger adults, many of which could have been prevented. Early
detection can save lives, but only when patients are supported at every step of the journey. What
makes the real difference is an approach that not only finds disease early, but also guides patients
through diagnosis, treatment, and follow-up without gaps or confusion. At Karkinos Healthcare, this
end-to-end support ensures that patients are not left to navigate cancer care on their own.
However, early detection alone is not enough. Finding disease early is valuable only if patients are
able to access timely, appropriate care. This is where women’s wellness becomes central to any
meaningful cancer strategy.
Across healthcare systems, women often face barriers—social, economic, and cultural—to seeking
care. Fear, stigma, lack of support, and competing family responsibilities frequently delay diagnosis.
By embedding early detection within a supportive, guided, and non-judgmental care pathway, we
move beyond simply identifying disease. We create an environment that encourages participation,
builds trust, and empowers women to prioritise their health. The journey then begins with clarity and
reassurance, rather than fear and uncertainty.

A Shared Need for Guidance

We often say, “each cancer journey is different.”  Biologically, this is true. Yet the human experience
of cancer reveals a universal truth: everyone needs guidance.
Throughout my career, my focus has been on making cancer care affordable, accessible, and
equitable. Karkinos Healthcare represents the next step in that mission. It is built on the idea that
compassion must be supported by systems, and that care must be coordinated, not fragmented.

Cancer care is not only about curing disease, but also about caring for people. When healthcare is
designed with compassion and purpose, patients need not walk alone—they are guided, supported,
and surrounded by a system that walks with them at every step of the journey.

About Dr. Paul Sebastian

Dr. Paul Sebastian is a senior cancer surgeon and public health leader with 40 years of experience in oncology, clinical governance, and population-level cancer programs. As a Leader in Clinical Operations &  Governance and Early Detection at Karkinos Healthcare, he drives quality, standardisation, and early diagnosis across large-scale cancer care initiatives. Former Director of RCC, Thiruvananthapuram, he was instrumental in its elevation as a State Cancer Institute and in building nationally recognised oncology training programs. A strong advocate of equitable and affordable cancer care, he has led multi-state outreach initiatives, served as principal investigator on major national and international studies, and authored 100+ peer-reviewed publications.

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